Drug intelligence / Profile preview

buyang huanwu decoction

Development stage
Phase 3
Lead developer
Affiliated Hospital of Southwest Medical University
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Buyang Huanwu Decoction (BYHWD) is a classic Traditional Chinese Medicine (TCM) formula first documented by Wang Qingren in the 19th-century text *Yi Lin Gai Cuo* (Corrections on the Errors of Medical Works). It is the representative prescription for treating 'Qi deficiency and blood stasis' syndrome, particularly during the recovery phase of ischemic stroke. The formula traditionally consists of seven herbal components: *Astragalus membranaceus* (Huangqi), *Angelica sinensis* (Dang-gui), *Paeonia lactiflora* (Chishao), *Ligusticum chuanxiong* (Chuanxiong), *Prunus persica* (Taoren), *Carthamus tinctorius* (Honghua), and *Pheretima aspergillum* (Dilong). Pharmacologically, BYHWD is recognized for its neuroprotective, anti-inflammatory, and pro-angiogenic properties. It is widely utilized in clinical practice and research for neurological disorders, cardiovascular diseases, and diabetic complications, where it is often integrated with Western medical treatments to improve motor function and microcirculation.

Brand names
Strocontrol
Other names
Bu-Yang-Huan-Wu TangBYHWTBYHWDBu-Yang-Huan-Wu-Tang补阳还五汤
02

Targets

VEGFA (Vascular endothelial growth factor A)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)

Beyond the preview

Go deeper on buyang huanwu decoction.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on buyang huanwu decoction.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call