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Buyang Huanwu Decoction (BYHWD) is a classic Traditional Chinese Medicine (TCM) formula first documented by Wang Qingren in the 19th-century text *Yi Lin Gai Cuo* (Corrections on the Errors of Medical Works). It is the representative prescription for treating 'Qi deficiency and blood stasis' syndrome, particularly during the recovery phase of ischemic stroke. The formula traditionally consists of seven herbal components: *Astragalus membranaceus* (Huangqi), *Angelica sinensis* (Dang-gui), *Paeonia lactiflora* (Chishao), *Ligusticum chuanxiong* (Chuanxiong), *Prunus persica* (Taoren), *Carthamus tinctorius* (Honghua), and *Pheretima aspergillum* (Dilong). Pharmacologically, BYHWD is recognized for its neuroprotective, anti-inflammatory, and pro-angiogenic properties. It is widely utilized in clinical practice and research for neurological disorders, cardiovascular diseases, and diabetic complications, where it is often integrated with Western medical treatments to improve motor function and microcirculation.
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