Drug intelligence / Profile preview

Buyang Huanwu decoction (First Affiliated Hospital of Henan University of Chinese Medicine)

Development stage
Unknown
Lead developer
First Affiliated Hospital of Henan University of Chinese Medicine
Modality
Peptides, Small Molecules
Administration
Oral
01

Overview

Buyang Huanwu decoction (BYHW) is a classic Traditional Chinese Medicine (TCM) herbal formula traditionally used to treat cardiovascular and cerebrovascular diseases, particularly ischemic heart failure (IHF) and stroke. The specific formulation evaluated by Zhu Mingjun at the First Affiliated Hospital of Henan University of Chinese Medicine consists of eight key ingredients: *Radix Astragali* (Huangqi), *Radix Angelicae Sinensis* (Danggui), *Radix Paeoniae Rubra* (Chishao), *Rhizoma Ligustici Chuanxiong* (Chuanxiong), *Salvia miltiorrhiza* (Danshen), *Semen Persicae* (Taoren), *Flos Carthami* (Honghua), and *Lumbricus* (Dilong). BYHW is indicated for patients presenting with 'Qi deficiency and blood stasis' syndrome according to TCM theory. Clinical research has demonstrated its potential to improve New York Heart Association (NYHA) classification, reduce NT-proBNP levels, and modulate energy metabolism and coagulation function in patients with IHF. Its mechanism of action involves multi-target modulation of angiogenesis, anti-inflammatory pathways, and myocardial energy metabolism.

Other names
Buyang Huanwu TangBYHWDYiqihuoxue prescription
02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)CAV1 (Caveolin-1)VEGFA (Vascular endothelial growth factor A)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)MYC (MYC proto-oncogene protein)TP53 (Cellular Tumor Antigen p53 R175H)MAP2K4 (Mitogen-activated protein kinase kinase 4)

Beyond the preview

Go deeper on Buyang Huanwu decoction (First Affiliated Hospital of Henan University of Chinese Medicine).

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Buyang Huanwu decoction (First Affiliated Hospital of Henan University of Chinese Medicine).

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call