Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
BVT-115959
- Development stage
- Phase 2
- Lead developer
- Sobi
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
BVT-115959 is a selective adenosine A2A receptor agonist developed for the oral treatment of pain, specifically targeting peripheral sites of inflammation and injury. The drug was designed to act preferentially at lower pH values found in inflamed tissues, thereby localizing its effect to sites of injury and reducing the risk of systemic side effects. It was investigated primarily for neuropathic and inflammatory pain conditions but development was discontinued after Phase II clinical trials due to insufficient efficacy or strategic reasons. The compound originated from Cambridge Biotechnology and was further developed by Swedish Orphan Biovitrum (Biovitrum)[1][5][6][10].
- Other names
- 2-O-methylisoguanosineadenosine 2-methoxy-adenosine2-methoxy-adenosine-2-methoxy-NSC-36899NSC36899NSC 36899
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADORA3 (Adenosine A3 receptor)
Beyond the preview
Go deeper on BVT-115959.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on BVT-115959.