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BWC6323

Development stage: Preclinical
Lead developer: Bugworks Research
Modality: Small Molecules
Administration: Oral

Overview

BWC6323 is a preclinical-stage small molecule dual inhibitor of cyclin-dependent kinase 7 (CDK7) and cyclin-dependent kinase 9 (CDK9), developed by Bugworks Research. It is designed to target cancers that exhibit transcriptional dependency, particularly MYC-driven, MCL1-dependent, and transcriptionally addicted solid tumors. By inhibiting both CDK7 and CDK9, BWC6323 aims to disrupt oncogenic transcription and cell-cycle progression, offering a potential therapeutic approach for cancers resistant to conventional cell-cycle or targeted therapies.

Targets

CDK9 (Cyclin-dependent kinase 9)CDK7

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