C-547

C-547 is a **macrocyclic 6-methyluracil derivative** that acts as a **potent, slow-binding, and highly selective acetylcholinesterase inhibitor**. It shows exceptional pharmacokinetic properties with long-lasting target engagement and tissue distribution. Unlike other cholinesterase inhibitors, C-547 is characterized by very slow elimination and an extended duration of action, owing to slow dissociation from its target and effective rebinding within the neuromuscular junction. It has been studied as a **potential treatment for myasthenia gravis** and is considered a promising drug lead for neuroprotection and other neurological indications[1][2].

Other names

C-547C547C 547