Drug intelligence / Profile preview

C20T5

Development stage
Unknown
Lead developer
Murdoch Children’s Research Institute
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

**C20T5** is a Cannatrek medicinal cannabis oral oil product marketed as a CBD-predominant formulation containing cannabidiol and delta-9-tetrahydrocannabinol. The product designation denotes a formulation containing approximately 20 mg/mL cannabidiol and 5 mg/mL delta-9-tetrahydrocannabinol. It was evaluated by Murdoch Childrens Research Institute in the randomized pilot trial NCT05615389 in children and young people receiving palliative care for non-oncological conditions. Its therapeutic activity is mediated principally through cannabinoid receptor signaling, with delta-9-tetrahydrocannabinol acting as a partial agonist at cannabinoid receptors 1 and 2, while cannabidiol has broader modulatory pharmacology across the endocannabinoid system and other signaling pathways.

Brand names
C20T5 Ruby CBD OilC-20T5 Ruby CBD OilC 20T5 Ruby CBD OilCannatrek C20T5 Ruby
Other names
C20T5C-20T5C 20T5
02

Targets

GABRR (GABA-A receptor subunit rho)GPR55 (G protein-coupled receptor 55)CNR2 (Cannabinoid receptor type 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)Glycine receptorFAAHHTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))PPARG (Peroxisome proliferator-activated receptor gamma)

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