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C402-CD19-CAR
- Development stage
- Phase 1
- Lead developer
- Formula 1
- Modality
- CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
- Administration
- Intravenous
01
Overview
C402-CD19-CAR is a rapid Point-Of-Care (rPOC) chimeric antigen receptor T (CAR-T) cell therapy developed by Shanghai Exuma Biotechnology. It is designed to target the CD19 antigen, which is expressed on the surface of most B-cell malignancies. The therapy involves engineering a patient's own T cells to express a CAR that recognizes and binds to CD19, leading to targeted destruction of malignant B cells. The primary indication under investigation for this therapy is relapsed or refractory large B-cell lymphoma[1][2].
- Other names
- C402 CD19 CARC-402 CD19 CARC 402 CD19 CAR
02
Targets
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