Drug intelligence / Profile preview

C62

Development stage
Preclinical
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics, Vaccines & Immunotherapeutics
Administration
Oral, Intramuscular
01

Overview

C62 is an investigational drug with two primary applications identified in the provided context. It functions as a potent neutralizing antibody specifically targeting the receptor binding domain S1B of the Porcine Epidemic Diarrhea Virus (PEDV)-S1 protein, demonstrating efficacy in inhibiting viral attachment and mitigating PEDV infection in piglets. Additionally, C62 is a key component of HIV-1 vaccine candidates, such as C62-M4 and C1C62-M3M4, which are being evaluated for their safety and immunogenicity in individuals with HIV-1 suppressed on antiretroviral therapy, aiming to enhance the immune system's ability to clear HIV from cells.

02

Targets

HIV (HIV-1 enzymes)PEDV-S1 (Porcine epidemic diarrhea virus spike protein S1 subunit)

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