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CA111 is an innovative, long-acting glucagon-like peptide-1 (GLP-1) receptor agonist developed by Chongqing Chenan Biological Pharmaceutical. It is primarily being developed for the treatment of obesity and overweight. As a GLP-1 receptor agonist, CA111 mimics the action of the endogenous hormone GLP-1, which regulates glucose metabolism and appetite. The drug works by stimulating insulin secretion in a glucose-dependent manner, inhibiting glucagon secretion, and delaying gastric emptying. Additionally, it targets the brain's appetite centers to promote satiety, leading to reduced caloric intake and subsequent weight loss. CA111 is currently undergoing Phase 2 clinical evaluation in China and represents a proprietary Class 1 innovative drug in the developer's metabolic pipeline.
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