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Drug intelligence / Profile preview
cabotegravir + rilpivirine and buprenorphine
- Development stage
- Unknown
- Lead developer
- ViiV Healthcare
- Modality
- Small Molecules
- Administration
- Intramuscular, Subcutaneous
01
Overview
This is not a single combination drug but rather two separate medications. Cabenuva is a complete regimen for HIV-1 treatment consisting of cabotegravir (an HIV-1 integrase strand transfer inhibitor) and rilpivirine (an HIV-1 non-nucleoside reverse transcriptase inhibitor) in an extended-release injectable suspension. Sublocade is an extended-release buprenorphine injection for the treatment of moderate to severe opioid use disorder. These medications are administered separately and are not formulated together as a single product.
- Brand names
- Cabenuva + Sublocade
- Other names
- cabotegravir + rilpivirine + buprenorphineCAB/RPV + XR-Blong-acting injectable HIV and OUD treatment
02
Targets
Integrase allosteric pocket (HIV)Human immunodeficiency virus type 1 reverse transcriptaseMOR (Mu opioid receptor)
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