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cacodylic acid
- Development stage
- Unknown
- Lead developer
- APC Holdings
- Modality
- Small Molecules
- Administration
- Topical, Inhalation
01
Overview
Cacodylic acid is an organoarsenic compound with the formula (CH3)2AsO2H. It is the simplest of the arsinic acids and appears as a colorless solid that is soluble in water. Cacodylic acid and its salts (notably sodium cacodylate) have been widely used as contact herbicides for defoliating or desiccating plants, including use during the Vietnam War as part of "Agent Blue." In addition to agricultural applications, sodium cacodylate serves as a buffering agent in biological sample preparation for electron microscopy and protein crystallography. The mechanism of action for its herbicidal effect involves disruption of plant metabolism due to arsenic toxicity[3][4][5]. Cacodylic acid has also been studied for mutagenicity and carcinogenicity; it can induce DNA damage in mammalian cells[5][6]. It is not primarily developed or marketed as a pharmaceutical drug. Developers: APC Holdings Corp
- Brand names
- Phytar
- Other names
- dimethylarsinic acidDMAsodium cacodylateAgent Blue
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