Drug intelligence / Profile preview

Caffeinol

Development stage
Unknown
Modality
Small Molecules
Administration
Intravenous, Oral
01

Overview

Caffeinol is a combination drug consisting of caffeine and ethanol, primarily investigated for its neuroprotective and anticonvulsive properties. It has been studied as a potential treatment for acute ischemic stroke and traumatic brain injury. Its mechanism of action is believed to involve antagonism of N-methyl-D-aspartate (NMDA) receptors, with caffeine augmenting the anti-ischemic effects of NMDA receptor blockers. Preclinical studies have shown Caffeinol to reduce cortical damage and improve neurological outcomes, and it has advanced to pilot clinical trials in humans for acute ischemic stroke.

Other names
caffeine and ethanolcaffeine and alcohol
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)

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