Drug intelligence / Profile preview

Cairo Univ. EGFR compound 7b

Development stage
Preclinical
Lead developer
Cairo University
01

Overview

Cairo Univ. EGFR compound 7b: sourced facts only. name: "Compound 7b effectively inhibited epidermal growth factor receptor (EGFR) with 50% inhibition concentration value (IC50 ) = 0.096 ± 0.004 compared to erlotinib with IC50 = 0.037 ± 0.002." [PMID:37357422]; target: "Compound 7b effectively inhibited epidermal growth factor receptor (EGFR) with 50% inhibition concentration value (IC50 ) = 0.096 ± 0.004 compared to erlotinib with IC50 = 0.037 ± 0.002." [PMID:37357422]; developer: "Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt." [PMID:37357422]; stage: "Furthermore, compound 7b raised total apoptosis by 21.93-fold in the ovarian cancer cell line (OVCAR-4) and caused an arrest in the cell cycle in the G1/S phase." [PMID:37357422]

02

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