Drug intelligence / Profile preview

cajuput oil

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Inhalation, Oral
01

Overview

Cajuput oil is a volatile essential oil obtained by steam distillation from the leaves and twigs of myrtaceous trees such as Melaleuca leucadendra and Melaleuca cajuputi. It is primarily composed of cineole (also known as eucalyptol), which imparts its characteristic odor similar to eucalyptus and camphor. Cajuput oil is used in traditional medicine for topical pain relief (as a counterirritant), treatment of colds, congestion, headaches, toothache, skin infections, minor wounds and rashes. Its mechanism of action when applied topically involves causing surface warmth and irritation through cineole-mediated vasodilation and sensory nerve stimulation. It is also an ingredient in some liniments (e.g., Tiger Balm) for sore muscles and in inhalants or decongestants[2][4][5]. Cajeput oil may interact with drugs metabolized by cytochrome P450 2D6 enzymes[1][3]. The majority of global production occurs in Indonesia.

Other names
cajeput oilcajuputumkayu putih oilmelaleuca leucadendra oilmelaleuca cajuputi oil
02

Targets

CYP2D6 (Cytochrome P450 2D6)

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