Drug intelligence / Profile preview

calamine + zinc oxide

Development stage
Unknown
Lead developer
Bailleul
Modality
Small Molecules
Administration
Topical
01

Overview

Calamine + zinc oxide is an approved topical combination drug developed by Laboratoires Bailleul (a subsidiary of Laboratoires de Monaco) for the treatment of skin irritations. Formulated as a gel containing 8% calamine and 8% zinc oxide, it acts through physical and chemical mechanisms on the skin surface without a specific molecular biological target. Zinc oxide serves as an anti-inflammatory and skin-protective agent, forming a barrier that reduces irritation and promotes skin regeneration, while calamine provides soothing and antipruritic (anti-itch) effects. It is approved as an over-the-counter adjunct treatment for irritant dermatitis, and is also used to relieve symptoms associated with chickenpox, insect bites, superficial burns, and other skin irritations.

Brand names
CalagelGel de Calamine BailleulGel de Calamine ThericaTherica Calamine Gel
Other names
calamine and zinc oxidecalamine/zinc oxidezinc oxide + calaminezinc oxide and calaminezinc oxide/calamine

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