Drug intelligence / Profile preview

Calcifar Plus

Development stage
Unknown
Lead developer
Farabi
Modality
Small Molecules
Administration
Oral
01

Overview

Calcifar Plus is an oral dietary supplement developed and manufactured by Farabi Pharmaceutical Company. Formulated as enteric-coated tablets, it contains a combination of essential minerals and vitamins, including calcium, magnesium, zinc, vitamin D3 (cholecalciferol), and vitamin K1 (phytomenadione). This combination is designed to support bone and teeth health, enhance bone matrix formation, and prevent bone loss associated with conditions like osteoporosis. Calcium and magnesium serve as critical structural components of bone, while zinc supports bone tissue repair and growth. Vitamin D3 promotes the absorption of calcium and phosphorus from the intestine and regulates bone mineralization through the activation of the vitamin D receptor (VDR). Vitamin K1 acts as an essential cofactor for gamma-glutamyl carboxylase (GGCX), facilitating the carboxylation and activation of osteocalcin, a key protein required for binding calcium to the bone matrix.

Brand names
Calcifar Plus
Other names
Ca, Mg, Zn, D3, K1Calcium + Magnesium + Zinc + Vitamin D3 + Vitamin K1calcium + magnesium + zinc + cholecalciferol + phytomenadione
02

Targets

CaSR (Extracellular calcium-sensing receptor)GGCX (Vitamin K-dependent gamma-glutamyl carboxylase)VDR (Vitamin D receptor)VKORC1 (Vitamin K epoxide reductase complex subunit 1)

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