Drug intelligence / Profile preview

CALCINASE EDTA-Lösung

Development stage
Unknown
Lead developer
lege artis Pharma
Modality
Small Molecules
Administration
Topical
01

Overview

CALCINASE EDTA-Lösung is a dental medical device (Class IIa) manufactured by lege artis Pharma for endodontic procedures. It contains a 20% solution of ethylenediaminetetraacetic acid (EDTA), specifically disodium edetate, which functions as a small molecule chelating agent. By binding to calcium ions in the hydroxyapatite of the dentin, it exerts a decalcifying effect that softens the root canal walls. This facilitates the location and widening of narrow or calcified canals and effectively removes the smear layer generated during mechanical preparation. It is typically used in alternating irrigation protocols with sodium hypochlorite to ensure thorough cleaning and disinfection of the root canal system.

Brand names
CALCINASE EDTA-LösungCALCINASE EDTA solution
Other names
20% EDTA solutiondisodium edetate solution
02

Targets

Hydroxyapatite

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