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CALCINASE EDTA-Lösung is a dental medical device (Class IIa) manufactured by lege artis Pharma for endodontic procedures. It contains a 20% solution of ethylenediaminetetraacetic acid (EDTA), specifically disodium edetate, which functions as a small molecule chelating agent. By binding to calcium ions in the hydroxyapatite of the dentin, it exerts a decalcifying effect that softens the root canal walls. This facilitates the location and widening of narrow or calcified canals and effectively removes the smear layer generated during mechanical preparation. It is typically used in alternating irrigation protocols with sodium hypochlorite to ensure thorough cleaning and disinfection of the root canal system.
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