calcipotriol + mometasone furoate

Calcipotriol + mometasone furoate is a topical combination drug formulated for the management of psoriasis. Calcipotriol is a synthetic vitamin D3 analog that regulates skin cell production and differentiation, while mometasone furoate is a potent corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictive properties. The combination leverages the complementary mechanisms of both agents to reduce inflammation, suppress immune responses in psoriatic lesions, and normalize keratinocyte proliferation. This binary mixture has been studied for its stability profile and efficacy in treating mild to moderate plaque psoriasis[1]. The combined use aims to enhance therapeutic outcomes compared to monotherapy with either agent.