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calcipotriol + tar
- Development stage
- Preclinical
- Lead developer
- LEO Pharma
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Calcipotriol + tar is a combination therapy used for the treatment of psoriasis. Calcipotriol is a synthetic vitamin D3 analog that works by slowing excessive skin cell production, enhancing cell differentiation, and affecting immunologic markers involved in psoriasis. Tar provides complementary anti-inflammatory and antiproliferative effects. This combination leverages the mechanisms of both agents to effectively manage psoriasis symptoms.
02
Targets
VDR (Vitamin D receptor)
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