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calcitriol + calcium carbonate + zinc sulfate (Elbrit Life Sciences)

Development stage: Unknown
Lead developer: Elbrit Life Sciences
Modality: Small Molecules
Administration: Oral

Overview

Calbrit CT is a fixed-dose combination oral tablet containing calcitriol (the active form of vitamin D3), calcium carbonate (providing elemental calcium), and zinc sulfate (providing elemental zinc). Developed by Elbrit Life Sciences, it is indicated for the prevention and treatment of calcium and vitamin D deficiencies, as well as supporting bone health in conditions such as osteoporosis, osteomalacia, and renal osteodystrophy. Calcitriol acts as a potent agonist of the vitamin D receptor to enhance intestinal calcium absorption, calcium carbonate directly supplies the essential mineral required for bone mineralization, and zinc serves as an essential cofactor for enzymes involved in bone matrix synthesis and osteoblast differentiation.

Brand names: Alfavit PlusCacaoCalbrit CTCalriseCalzemCalzowelE-CAMGemsolineHhcal-TrolIfycal-CTJee-Cal PlusOnecallOstonexOzocalSelza-C
Other names: calcitriol + calcium carbonate + zinccalcitriol + elemental calcium + elemental zinccalcitriol + elemental calcium + zinc sulfate

Targets

PDIA3 (Membrane-associated rapid response steroid-binding receptor)CaSR (Extracellular calcium-sensing receptor)VDR (Vitamin D receptor)

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