Drug intelligence / Profile preview

calcium chloride + dextrose + potassium chloride + sodium lactate + sodium chloride

Development stage
Approved
Lead developer
Pfizer
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

**Calcium chloride + dextrose + potassium chloride + sodium lactate + sodium chloride** is a parenteral combination electrolyte and carbohydrate crystalloid solution marketed as **Lactated Ringer's and Dextrose Injection**. It is an intravenous fluid replacement product used to provide water, electrolytes, and calories, and to help correct mild metabolic acidosis through the alkalinizing effect of sodium lactate metabolism. The formulation combines sodium and chloride for extracellular fluid replacement, potassium and calcium for electrolyte replenishment, lactate as a bicarbonate precursor, and dextrose as a carbohydrate calorie source and blood glucose substrate. It is a pharmaceutical small-molecule mineral/electrolyte solution rather than a biologic, and has been manufactured by Hospira, now part of Pfizer, for fluid and electrolyte replacement and related supportive care indications in adults and pediatric patients.

Brand names
Lactated Ringer's and Dextrose InjectionLactated Ringer's and Dextrose Injection USPLactated Ringer's and Dextrose 5% InjectionPotassium Chloride in Lactated Ringer's and Dextrose 5% Injection
Other names
calcium chloride + dextrose + potassium chloride + sodium lactate + sodium chloridelactated ringer's and dextroselactated ringer's and dextrose injectionlactated ringer's and dextrose 5% injectiondextrose in lactated ringer'sdextrose lactated ringer'sringer's lactate and dextrose

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