Drug intelligence / Profile preview

calcium chloride + potassium chloride + sodium chloride + sodium lactate + dextrose

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous
01

Overview

**Calcium chloride + potassium chloride + sodium chloride + sodium lactate + dextrose** is a sterile intravenous crystalloid and carbohydrate combination solution corresponding to Lactated Ringer's with dextrose. It is used as a parenteral source of water, electrolytes, and calories, and also exerts an alkalinizing effect because lactate is metabolized to bicarbonate. The product is used for extracellular fluid replacement, electrolyte replenishment, and limited caloric support in adults and pediatric patients who require intravenous hydration or resuscitative support. It is a multi-ingredient small molecule formulation rather than a target-directed therapy, with pharmacologic activity arising from restoration of circulating fluid volume, sodium, potassium, calcium, chloride, and buffer precursor balance rather than interaction with a discrete molecular target.

Brand names
Lactated Ringer's and Dextrose Injection
Other names
calcium chloride + potassium chloride + sodium chloride + sodium lactate + dextroselactated ringer's and dextrosedextrose in lactated ringer'slactated ringer's and dextrose 5%potassium chloride in lactated ringer's and dextrose injection

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