Drug intelligence / Profile preview

calcium chloride + sodium chloride + sodium lactate + potassium chloride

Development stage
Unknown
Lead developer
Takeda
Modality
Small Molecules
Administration
Intravenous, Topical
01

Overview

**Calcium chloride + sodium chloride + sodium lactate + potassium chloride** is a fixed-combination isotonic crystalloid electrolyte solution commonly known as **lactated ringer's solution** or **Hartmann's solution**. It is a **small molecule** parenteral fluid and electrolyte replacement product used as a source of water and electrolytes and as an alkalinizing agent in adults and pediatric patients; irrigation formulations are also used for general washing, rinsing, and arthroscopic procedures. Its therapeutic effect is not mediated through a discrete receptor target, but through physiologic replacement of extracellular fluid components: sodium and chloride help restore intravascular and interstitial volume, potassium and calcium help replenish essential electrolytes, and lactate is metabolized to bicarbonate, which can help buffer metabolic acidosis. It is a long-established hospital product manufactured by multiple companies, including B. Braun and Baxter, and is used for dehydration, extracellular fluid loss, electrolyte imbalance, and related supportive care settings.

Brand names
Lactated Ringer's InjectionLactated Ringer's IrrigationHartmann's solutionRinger's lactate solution
Other names
calcium chloride + sodium chloride + sodium lactate + potassium chloridelactated ringer's solutionringer lactatelactated ringer'shartmann solution

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