Drug intelligence / Profile preview

calcium chloride + sodium lactate + magnesium chloride + sodium chloride + dextrose

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

A sterile, non-pyrogenic **peritoneal dialysis solution** containing **calcium chloride, sodium lactate, magnesium chloride, sodium chloride, and dextrose**. It has been developed and marketed by **Baxter** in products such as **DIANEAL Low Calcium** and **DELFLEX** for **intraperitoneal** use in patients with **acute or chronic renal failure** and **chronic kidney failure** requiring peritoneal dialysis. The product is a **multi-ingredient electrolyte and carbohydrate formulation** rather than a targeted molecular therapeutic: **dextrose** creates an osmotic gradient that promotes ultrafiltration and removal of waste solutes across the peritoneal membrane, while the electrolyte components and lactate buffer help maintain fluid, acid-base, and electrolyte balance during dialysis. It is an approved pharmaceutical dialysis solution, not a biologic, and its therapeutic effect derives from restoration and manipulation of physiologic fluid composition rather than binding to a single specific molecular target.

Brand names
DIANEAL Low CalciumDELFLEX
Other names
peritoneal dialysis solutionlow magnesium low calcium peritoneal dialysis solutiondextrose monohydrate + sodium chloride + sodium lactate + calcium chloride + magnesium chloride

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