Drug intelligence / Profile preview

calcium chloride + sodium lactate + magnesium chloride + sodium chloride + dextrose monohydrate

Development stage
Approved
Lead developer
Takeda
Modality
Small Molecules
Administration
Intraperitoneal
01

Overview

**Calcium chloride + sodium lactate + magnesium chloride + sodium chloride + dextrose monohydrate** is a multi-ingredient **peritoneal dialysis solution** used for intraperitoneal dialysis in patients with acute or chronic renal failure, including chronic kidney failure. It is a sterile electrolyte and osmotic agent formulation in which dextrose monohydrate provides the osmotic driving force for ultrafiltration, while sodium, calcium, magnesium, chloride, and lactate help maintain acid-base and electrolyte balance during dialysis. The solution acts locally across the **peritoneal membrane**, which serves as the semipermeable dialysis interface for removal of water and uremic solutes. Public context provided identifies the marketed product **DIANEAL LOW CALCIUM WITH DEXTROSE**, with manufacturing/distribution associated with **Vantive** and **Baxter**.

Brand names
DIANEAL LOW CALCIUM WITH DEXTROSE
Other names
DIANEAL peritoneal dialysis solutionperitoneal dialysis solution

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