Drug intelligence / Profile preview

calcium chloride + sodium lactate + potassium chloride + dextrose monohydrate + sodium chloride

Development stage
Approved
Lead developer
ICU Medical
Modality
Small Molecules
Administration
Intravenous, Parenteral
01

Overview

This drug is a **sterile intravenous crystalloid and carbohydrate replacement solution** containing **sodium chloride, sodium lactate, potassium chloride, calcium chloride, and dextrose monohydrate**. Marketed as **Lactated Ringer's and Dextrose (5%) Injection**, it is used as a source of **water, electrolytes, and calories** and as an **alkalinizing agent** in adults and pediatric patients. Its pharmacologic effect is not mediated through a single discrete receptor; rather, it restores extracellular fluid volume and electrolyte composition, while the **lactate** component is metabolized to bicarbonate precursors that help buffer metabolic acidosis and the **dextrose** provides minimal caloric support. Public labeling and product information identify ICU Medical as a current commercial source, with historical Hospira labeling also associated with the product.

Brand names
Lactated Ringer's and DextroseLactated Ringer's and 5% Dextrose InjectionLactated Ringer's and Dextrose (5%) Injection
Other names
calcium chloride + sodium lactate + potassium chloride + dextrose monohydrate + sodium chloridedextrose in lactated ringersdextrose in lactated ringer'ssodium chloride + sodium lactate + potassium chloride + calcium chloride + dextrose monohydratelactated ringer's and 5% dextrose

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