Drug intelligence / Profile preview

calcium citrate malate + cholecalciferol

Development stage: Unknown
Lead developer: Achilles Healthcare
Modality: Small Molecules
Administration: Oral

Overview

Calcilate-D is an approved combination product developed by Achilles Healthcare, formulated to support bone health and mineral homeostasis. It contains calcium citrate malate, a water-soluble calcium source known for its high bioavailability compared to other calcium salts, and vitamin D3 (cholecalciferol). Calcium is a critical structural component of bone tissue, while vitamin D3 acts as a precursor to calcitriol, which binds to the vitamin D receptor (VDR) to enhance intestinal calcium absorption and regulate renal calcium excretion. This product is primarily used for the treatment and prevention of calcium and vitamin D deficiencies, and as an adjunct therapy for osteoporosis.

Brand names: Calcilate-D
Other names: Calcium citrate malate + Vitamin D3Calcium citrate malate + Cholecalciferol

Targets

CaSR (Extracellular calcium-sensing receptor)VDR (Vitamin D receptor)

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