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calcium dobesilate (CSL Vifor)
- Development stage
- Phase 1
- Lead developer
- Vifor Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Calcium dobesilate (calcium hydroxybenzene sulphonate) is a synthetic vasoprotective agent primarily used to treat microvascular disorders, including diabetic retinopathy and chronic venous insufficiency. It acts by improving capillary resistance, reducing capillary permeability, and decreasing blood viscosity. Additionally, it enhances lymphatic drainage and exhibits anti-inflammatory and antioxidant properties by modulating the activity of various mediators such as histamine, bradykinin, and vascular endothelial growth factor (VEGF). Originally developed by Laboratoires OM (now Vifor Pharma), it is marketed under the brand name Doxium and is available in various oral formulations, including tablets and capsules.
- Brand names
- DoxiumDobesilDexiumDoxilek
- Other names
- calcium hydroxybenzene sulphonatecalcium hydroxybenzene sulfonatecalcium 2,5-dihydroxybenzenesulfonatecalcium dobesilate
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