Drug intelligence / Profile preview

calcium glycerophosphate

Development stage
Approved
Lead developer
AkPharma
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Calcium glycerophosphate is a calcium salt of glycerophosphoric acid used as a mineral salt and acid-neutralizing agent. Public sources identify it both as the active ingredient in AkPharma's Prelief products, which are marketed to reduce the acidity of foods and beverages, and as the investigational ingredient in an AkPharma intranasal wash studied for symptomatic relief of allergic rhinitis. Mechanistically, it does not act through a well-defined receptor target; rather, it functions primarily through physicochemical buffering and mineral supplementation, providing calcium and phosphate/glycerophosphate and reducing acidity in the local environment. It is best characterized as a small-molecule mineral salt rather than a targeted pharmaceutical asset. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT01647633))

Brand names
PreliefCal-Phos
Other names
calcium glycerophosphatecalcium glycerylphosphateglycerophosphoric acid calcium saltcalcium 2-glycerophosphatecalcium2-glycerophosphatecalcium-2-glycerophosphate

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