Drug intelligence / Profile preview

calcium hydroxylapatite + lidocaine

Development stage
Unknown
Lead developer
Merz
Modality
Small Molecules
Administration
Subdermal
01

Overview

Calcium hydroxylapatite + lidocaine is an injectable soft tissue filler formulation combining synthetic calcium hydroxylapatite (CaHA) microspheres suspended in a gel carrier with 0.3% lidocaine. The lidocaine component is included to reduce pain and discomfort during the injection procedure. The product is primarily indicated for subdermal implantation to correct moderate-to-severe facial wrinkles and folds (such as nasolabial folds). The CaHA microspheres provide immediate volume correction and stimulate endogenous collagen production (neocollagenesis), resulting in long-lasting results for facial rejuvenation and volume restoration. The addition of lidocaine does not alter the performance, safety, or aesthetic efficacy of the filler, and is associated with significantly reduced pain ratings during and after injection[2][4][9][7].

Brand names
Radiesse (+)
Other names
CaHA(+)calcium hydroxylapatite with integral lidocainecalcium hydroxyapatite + lidocaine
02

Targets

NaV (Voltage-gated sodium channels)

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