calcium levulinate

Calcium levulinate is a relatively new, highly bioavailable organic salt of calcium derived from the reaction of levulinic acid and calcium hydroxide. It is used as a pharmaceutical preparation for treating acute or chronic hypocalcemia and other conditions requiring rapid elevation of serum calcium levels. The compound features high solubility (over 30% at 25°C), neutral pH, and low irritation potential, making it suitable for oral, parenteral (injection/infusion), and food fortification applications. Calcium levulinate provides approximately 14.8% more elemental calcium than commonly used alternatives like calcium lactate. Its mechanism involves dissociation in the gastrointestinal tract or bloodstream to release free Ca2+ ions, which are then absorbed to replenish body stores[1][2][5][6][7]. Calcium levulinate is also widely used as a food fortifier in beverages, dairy products, soy products, sauces, and other foods due to its high solubility and stability[1][2][3][4]. It is considered non-toxic and non-allergenic with good taste profile[5]. No specific brand names were identified; it is generally marketed under its generic name.

Other names

calcium levulinate dihydrate