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calcium polycarbophil + loperamide + oxycodone hydrochloride hydrate
- Development stage
- Unknown
- Lead developer
- Foundation Consumer Brands
- Modality
- Small Molecules, Biodegradable Polymers → Polymer-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Oral
01
Overview
This is a combination drug containing three active ingredients: - **Calcium polycarbophil** is a bulk-forming laxative and stool stabilizer used to treat constipation, irritable bowel syndrome, or diarrhea. It works by increasing the bulk and water content of stool, promoting intestinal movement and softer stools[4][6]. - **Loperamide** is a synthetic opioid antidiarrheal agent that acts on the gut wall to reduce peristalsis and increase transit time, thereby reducing diarrhea[2]. - **Oxycodone hydrochloride hydrate** is an opioid analgesic indicated for moderate to severe pain. It acts primarily as an agonist at the mu-type opioid receptor in the central nervous system to produce analgesia[1]. This combination would theoretically provide symptomatic relief for patients experiencing both pain (oxycodone), diarrhea (loperamide), and/or constipation/irregularity (calcium polycarbophil). However, this specific triple combination does not appear as a marketed product; it combines agents with potentially opposing gastrointestinal effects.
- Other names
- calcium polycarbophil + loperamide + oxycodone hydrochloride hydrate
02
Targets
MOR (Mu opioid receptor)
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