Drug intelligence / Profile preview

calcium silicate

Development stage
Phase 1
Lead developer
Ain Shams University
Modality
Small Molecules
Administration
Topical
01

Overview

Calcium silicate is a bioceramic material utilized as an intracanal medication in endodontic procedures, particularly for the treatment of periapical lesions and abscesses. In clinical settings, such as those evaluated by Ain Shams University, it is used as an inter-visit dressing to disinfect the root canal system and promote tissue repair. The material functions through a hydration reaction that releases calcium hydroxide, leading to a high alkaline pH and the subsequent formation of hydroxyapatite. These properties contribute to its high biocompatibility, bioactivity, and effective antimicrobial action against resistant microorganisms. A prominent commercial example of this medication is Bio-C Temp, which is formulated for easy application and removal within the root canal.

Brand names
Bio-C Temp
Other names
calcium silicate-based bioceramicbioceramic intracanal medicationcalcium silicate intracanal medication

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