Drug intelligence / Profile preview

Calmagrip Forte

Development stage
Unknown
Lead developer
Pharmex Group
Modality
Small Molecules
Administration
Oral
01

Overview

Calmagrip Forte is an oral combination medication developed and marketed by Pharmex Group for the symptomatic relief of common cold and influenza symptoms. It contains three active ingredients: paracetamol (650 mg), which acts as an analgesic and antipyretic; caffeine (25 mg), which serves as a central nervous system stimulant and adjuvant to enhance paracetamol's effects; and chlorphenamine maleate (4 mg), an H1 antihistamine that alleviates allergic symptoms such as sneezing, tearing, and nasal congestion. The product is approved in Spain for treating fever, mild to moderate pain, and catarrhal processes associated with the common cold and flu.

Brand names
Calmagrip Forte
Other names
Paracetamol/Caffeine/Chlorphenamine 650mg/25mg/4mgparacetamol + caffeine + chlorphenamine
02

Targets

ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)HRH1 (Histamine H1 Receptor)

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