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Calmante Vitaminado
- Development stage
- Unknown
- Lead developer
- Laboratorios Combix
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Calmante Vitaminado is an over-the-counter (OTC) combination analgesic and vitamin supplement marketed by Laboratorios Combix in Spain. It contains acetylsalicylic acid (aspirin), caffeine, and thiamine hydrochloride (vitamin B1). Acetylsalicylic acid provides analgesic and antipyretic effects by inhibiting cyclooxygenase enzymes, while caffeine acts as an adjuvant to enhance the pain-relieving properties. Thiamine is included as a nutritional supplement. The product is indicated for the symptomatic relief of occasional mild to moderate pain, such as headaches, dental pain, menstrual pain, and muscle aches, as well as for the reduction of fever. Originally a product of Laboratorios Pérez Giménez, it was relaunched by Combix in 2022.
- Brand names
- Calmante VitaminadoCalmante Vitaminado PerezGiménez
- Other names
- ASA/Caffeine/Vitamin B1 500mg/50mg/2mgASA + caffeine + thiamine
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ADORA2A (Adenosine A₂A Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)ADORA1 (Adenosine receptor A1 subtype)
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