Drug intelligence / Profile preview

Calmoseptine

Development stage
Phase 4
Lead developer
Calmoseptine
Modality
Small Molecules
Administration
Topical
01

Overview

Calmoseptine is a multi-purpose moisture barrier ointment originally developed by a pharmacist for use as a diaper rash treatment. It contains zinc oxide and menthol as its primary active ingredients. Zinc oxide acts as a skin protectant and mild astringent, providing a physical barrier against moisture and irritants such as urine and feces. Menthol serves as a topical analgesic and antipruritic, providing a cooling sensation and relieving pain and itching associated with skin irritation. The formulation is widely used in clinical settings for the prevention and treatment of incontinence-associated dermatitis (IAD), skin tears, and protection around feeding tube sites or wound drainage areas.

Brand names
Calmoseptine
Other names
CaladroxChamosynLantiseptic Multi-PurposeRemedy CalazimeRisamineDermaSeptin
02

Targets

TRPM8 (Transient receptor potential cation channel subfamily M member 8)

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