cam1615SS1

cam1615SS1 is a **research-stage mesothelin-targeted trispecific killer engager** designed to redirect and potentiate natural killer cell antitumor activity against **mesothelin-expressing solid tumors**, especially non-small cell lung cancer. The construct is a **trispecific recombinant biologic** that binds **mesothelin** on tumor cells and **CD16** on natural killer cells while incorporating an **interleukin-15** moiety to promote natural killer cell activation, proliferation, survival, and cytotoxic function. It has been reported in preclinical work from the **University of Minnesota** and collaborators including investigators associated with the **National Cancer Institute**, and appears to remain in **preclinical or very early research development** without an identified commercial brand name or established commercial sponsor.

Other names

mesothelin-targeted trispecific killer engagermesothelin-targeted TriKEmesothelin-targeted trispecific killer engager TriKE