Drug intelligence / Profile preview

CAM2028

Development stage
Unknown
Lead developer
Camurus
Modality
Small Molecules
Administration
Topical
01

Overview

**CAM2028** is a Camurus-developed, topical bioadhesive lipid formulation designed to relieve pain from oral mucositis. Phospholipid and triglyceride components spread across the oral mucosa and self-assemble with small amounts of saliva into a liquid-crystalline protective lining, providing rapid mechanical shielding of ulcerated mucosa. In the investigational **CAM2028-benzydamine** version, the formulation locally delivered benzydamine hydrochloride, a non-steroidal anti-inflammatory small molecule; however, the unmedicated CAM2028 control provided similar analgesia in a randomized crossover Phase 2 study, indicating that barrier formation was the principal observed contributor to pain relief. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC4008777/)) The unmedicated commercial product derived from this platform is marketed as Episil and is regulated as a non-absorptive oral medical device rather than as the benzydamine-containing investigational formulation. ([solasia.co.jp](https://solasia.co.jp/en/pipeline/sp03.html))

Other names
CAM2028-controlCAM-2028-controlCAM 2028-control

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