Drug intelligence / Profile preview

CAM2032

Development stage
Phase 2
Lead developer
Camurus
Modality
Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules
Administration
Subcutaneous
01

Overview

CAM2032 is a **long-acting subcutaneous depot formulation** of leuprolide acetate, delivered using Camurus' proprietary FluidCrystal technology for **monthly self-administration** via a prefilled syringe. It is being developed primarily for **prostate cancer**, with additional development for **endometriosis** and **precocious puberty**. CAM2032 provides a fast onset and sustained release of leuprolide, an agonist analog of gonadotropin-releasing hormone (GnRH), resulting in suppression of testosterone secretion and tumor progression in hormone-dependent conditions. Clinical studies show comparable safety and pharmacodynamics to standard leuprolide depots, with higher bioavailability and good tolerability. Developed by Camurus.

Other names
Leuprolide Acetate FluidCrystal Injection Depot
02

Targets

GnRHR (Gonadotropin-releasing hormone receptor)

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