Drug intelligence / Profile preview

camellia oil

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Oral
01

Overview

Camellia oil is a natural plant-derived oil extracted from the seeds of various Camellia species, most commonly Camellia oleifera and Camellia japonica. It is rich in unsaturated fatty acids (notably oleic acid and linoleic acid), vitamins (A, B, C, D, E), squalene, polyphenols, and minerals. The primary mechanism of action is its emollient effect—camellia oil deeply hydrates skin and hair by mimicking the skin’s natural sebum composition. Its bioactive compounds exhibit anti-inflammatory activity by disrupting NF-κB signaling pathways to reduce pro-inflammatory cytokines; antioxidant effects are mediated through squalene and tocopherol scavenging free radicals; it also inhibits metalloproteinases involved in collagen degradation via flavonoids like kaempferol[2][4]. Topically applied camellia oil supports skin barrier function (reducing transepidermal water loss), soothes irritation/redness (including acne-prone or sensitive skin), improves elasticity/firmness by stimulating collagen production, reduces hyperpigmentation by inhibiting melanin synthesis[4][6], strengthens nails/cuticles[3], conditions hair/lashes/scalp for improved growth and shine[1][7]. It is widely used in cosmetics for facial care products (serums/oils/creams/masks), body care products (lotions/massage oils/soaps/nail serums), as well as haircare formulations.

Other names
camellia seed oiltea seed oilCamellia oleifera oilCamellia japonica oil
02

Targets

TYR (Tyrosinase)

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