Drug intelligence / Profile preview

Camphor

Development stage
Phase 4
Modality
Small Molecules
Administration
Topical, Inhalation
01

Overview

Camphor is a natural or synthetic terpene, a white crystalline substance with a strong, aromatic odor. It is widely utilized as a topical medication, primarily functioning as a counterirritant and mild analgesic. When applied to the skin, it stimulates nerve endings, producing sensations of warmth or coolness that help to distract from underlying pain and itching. Camphor is FDA-approved for topical use to relieve pain, itching, and cough suppression. Beyond its analgesic and counterirritant effects, it also possesses anti-inflammatory and antimicrobial properties. Its mechanism of action involves modulating various transient receptor potential (TRP) channels, contributing to its diverse therapeutic effects.

Brand names
Vicks VapoRubTiger BalmIcy HotBengaySarnaJointFlexBenadryl Anti-ItchSalonpas Pain Relieving PatchVicks VapoSteam
Other names
Cinnamomum camphoracamphire2-CamphanoneAnemone CamphorFormosa CamphorGum CamphorKampferLaurel CamphorMatricaria Camphor
02

Targets

TRPV3 (Transient receptor potential vanilloid subtype 3)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPA1 (Transient receptor potential cation channel subfamily A member 1)

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