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camphor + diclofenac sodium + menthol
- Development stage
- Unknown
- Lead developer
- Puretek
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
A topical combination drug containing **diclofenac sodium**, **camphor**, and **menthol**, predominantly formulated as a gel or solution for localized relief of musculoskeletal pain, osteoarthritis, and related inflammatory conditions. Diclofenac sodium is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase enzymes (COX-1 and COX-2), thus reducing prostaglandin synthesis and exerting anti-inflammatory, analgesic, and antipyretic effects. Camphor and menthol are counterirritants; camphor provides a cooling sensation and mild local anesthetic action, while menthol activates cold-sensitive TRPM8 receptors, leading to a cooling effect and mild analgesia. This combination is used topically to reduce pain, swelling, and stiffness in conditions like osteoarthritis, muscle sprains, and tendonitis.
- Brand names
- DiclogenCampor/Diclofenac/Menthol KitInflatherm
- Other names
- diclofenac + capsaicin + menthol + camphordiclofenac sodium + methyl salicylate + menthol + camphor
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)TRPA1 (Transient receptor potential cation channel subfamily A member 1)PGHS-1 (Prostaglandin G/H Synthase 1)
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