Drug intelligence / Profile preview

camphor oil

Development stage
Unknown
Modality
Small Molecules
Administration
Topical, Inhalation
01

Overview

Camphor oil is an essential oil distilled from the wood of the camphor tree (*Cinnamomum camphora*) and contains camphor as its primary active component[6]. It is used topically as an antipruritic (to relieve itching), analgesic (to relieve pain), anti-infective, and anti-inflammatory agent[1][4][6]. Camphor oil is also employed for its decongestant effects (in vapor rubs for chest congestion and cough), antispasmodic properties for muscle cramps, and as an antifungal and antibacterial agent[2][3][6][8]. Its mechanism of action involves stimulation of sensory nerve endings, producing a cooling, warming, and numbing effect that leads to symptom relief[8]. Camphor oil is widely used in aromatherapy, personal care, natural home cleaning, and as a natural insect repellent[6]. Only the "white" grade of camphor oil is considered safe for medicinal and aromatic use; the FDA has banned concentrated camphorated oils due to toxicity risks, setting a topical maximum of 11% camphor in products[5][6].

Other names
camphor essential oilcamphorated oilgum camphortrue camphorcommon camphorFormosa camphorwhite camphor oilcamphor liniment
02

Targets

TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)TRPV3 (Transient receptor potential vanilloid subtype 3)

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