Drug intelligence / Profile preview

Canal-S

Development stage
Unknown
Lead developer
GC Biopharma
Modality
Small Molecules
Administration
Intracanal
01

Overview

Canal-S is a dental medical device used as a root canal filling material (sealer) in endodontic procedures. Developed and marketed by GC Showa Yakuhin, it is typically used in conjunction with gutta-percha points to provide a permanent seal for the root canal system after cleaning and shaping. The product functions as a zinc oxide-guaiacol based sealer, providing antimicrobial properties and ensuring a fluid-tight seal to prevent reinfection of the periapical tissues. It is a long-standing product in the Japanese dental market, classified as a dental material for permanent obturation.

Brand names
Canal-S
Other names
Canal-S (endodontic product)キャナール-S
02

Targets

GYS1 (Glycogen synthase 1)GYS2 (Glycogen synthase 2)SDH (Mitochondrial electron transport chain complex II)

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