Drug intelligence / Profile preview

Cancer Vaccine + CARvac

Development stage
Preclinical
Lead developer
BioNTech
Modality
Cell Therapies, Gene Therapies, Vaccines & Immunotherapeutics
Administration
Intravenous
01

Overview

Cancer Vaccine + CARvac is a preclinical-stage oncology therapeutic being developed by Shanghai BDgene Therapeutics. It utilizes the company's proprietary BD-VLP (virus-like particle) platform to deliver a combined cancer vaccine and CAR-based (Chimeric Antigen Receptor) therapeutic approach, often referred to as a CAR-T cell amplifying vaccine (CARvac). The program is designed to treat solid tumors by enhancing the activity and persistence of CAR-T cells through vaccination. While the specific antigen targets and transgenes have not been publicly disclosed, the therapy leverages the BD-VLP system's ability to deliver mRNA or gene-editing components to modulate the immune response against cancer cells.

Other names
Cancer VaccineCARvacBD-VLP cancer vaccineCancer Vaccine/CARvac
02

Targets

CLDN6 (Claudin-6)

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