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Drug intelligence / Profile preview
Cancer Vaccine + CARvac
- Development stage
- Preclinical
- Lead developer
- BioNTech
- Modality
- Vaccines & Immunotherapeutics, Cell Therapies, Gene Therapies
- Administration
- Intravenous
01
Overview
Cancer Vaccine + CARvac is a preclinical-stage oncology therapeutic being developed by Shanghai BDgene Therapeutics. It utilizes the company's proprietary BD-VLP (virus-like particle) platform to deliver a combined cancer vaccine and CAR-based (Chimeric Antigen Receptor) therapeutic approach, often referred to as a CAR-T cell amplifying vaccine (CARvac). The program is designed to treat solid tumors by enhancing the activity and persistence of CAR-T cells through vaccination. While the specific antigen targets and transgenes have not been publicly disclosed, the therapy leverages the BD-VLP system's ability to deliver mRNA or gene-editing components to modulate the immune response against cancer cells.
- Other names
- Cancer VaccineCARvacBD-VLP cancer vaccineCancer Vaccine/CARvac
02
Targets
CLDN6 (Claudin-6)
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