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Candenizumab is an investigational drug being studied for the treatment of HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma. It is currently being evaluated in combination with lenvatinib and the SOX chemotherapy regimen (S-1 plus oxaliplatin) in clinical trials. The precise mechanism of action, molecular target, and modality of candenizumab have not been publicly disclosed as of June 2025. Its development appears to be led by academic institutions rather than a pharmaceutical company, with Fujian Medical University listed as a lead sponsor in clinical research[5].
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