Drug intelligence / Profile preview

Candex

Development stage
Unknown
Lead developer
Bristol Myers Squibb
Modality
Small Molecules
Administration
Oral, Topical, Vaginal
01

Overview

Candex is a brand name used for antifungal medications, most commonly containing nystatin or clotrimazole, depending on the regional market. In its nystatin formulation (e.g., as marketed by Adcock Ingram), it is a polyene antifungal derived from *Streptomyces noursei*. It is indicated for the treatment of localized *Candida* infections, such as oral thrush, cutaneous candidiasis, and intestinal infections. The drug works by binding to ergosterol in the fungal cell membrane, creating transmembrane pores that lead to the leakage of essential intracellular components and subsequent cell death. Because nystatin is not significantly absorbed through the skin or mucous membranes, Candex is primarily used for local effect. It is important to note that 'Candex' is also the name of a popular enzyme-based dietary supplement used for yeast management, which is a distinct non-pharmaceutical product.

Brand names
Candex
Other names
nystatin
02

Targets

Ergosterol

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