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cannabidiol + tetrahydrocannabinol (PsyLabs)
- Development stage
- Preclinical
- Lead developer
- PsyLabs
- Modality
- Small Molecules
- Administration
- Inhalation
01
Overview
PsyLabs' cannabidiol (CBD) and tetrahydrocannabinol (THC) pre-roll is a pharmaceutical-grade smokable product derived from plant extract distillate. Produced by PsyLabs, a South African API manufacturer, this product is designed for use in clinical trials and research settings. THC primarily functions as a partial agonist at the Cannabinoid receptor 1 (CB1) and Cannabinoid receptor 2 (CB2), mediating psychoactive and analgesic effects. CBD exhibits a complex pharmacological profile, acting as a negative allosteric modulator of the CB1 receptor and an agonist at the 5-HT1A serotonin receptor and TRPV1 vanilloid receptor. The combination is often utilized to leverage the "entourage effect" or to mitigate the psychoactive side effects of THC.
- Other names
- CBD/THC pre-rollsCBD/THC distillate pre-rollcannabidiol + tetrahydrocannabinol-PsyLabs-plant extract-distillate-smokable product (pre-roll)
02
Targets
CNR2 (Cannabinoid receptor type 2)TRPV1 (Transient receptor potential cation channel subfamily V member 1)HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))
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