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cannabidiol and aspartame topical formulation
- Development stage
- Unknown
- Lead developer
- Jupiter Wellness
- Modality
- Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
- Administration
- Topical
01
Overview
JW-100 is a novel topical drug formulation that combines cannabidiol (CBD) and aspartame. It is being developed for the treatment of atopic dermatitis (eczema). In clinical studies, JW-100 demonstrated statistically significant improvements in Investigator's Static Global Assessment (ISGA) scores after 14 days of use compared to CBD alone or placebo, with 50% of patients achieving clear or almost clear skin. The mechanism of action is believed to involve the anti-inflammatory properties of cannabidiol, though the specific molecular targets are not fully detailed. The product is under development by Jupiter Wellness and has been evaluated in randomized, double-blind, placebo-controlled trials for mild to moderate eczema[1][3][5][7].
- Brand names
- JW-100JW100JW 100
- Other names
- JW-100JW100JW 100
02
Targets
CNR1 (Cannabinoid receptor 1)TAS1R2 (Taste receptor type 1 member 2)
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