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Drug intelligence / Profile preview
cannabidiol-enriched cannabis oil
- Development stage
- Phase 3
- Lead developer
- Panaxia Pharmaceuticals
- Modality
- Small Molecules
- Administration
- Oral, Sublingual
01
Overview
Cannabidiol-enriched cannabis oil is a pharmaceutical-grade phytocannabinoid formulation developed by Panaxia Pharmaceuticals for the treatment of intractable pediatric epilepsy. The formulation typically consists of a 20:1 ratio of cannabidiol (CBD) to tetrahydrocannabinol (THC) dissolved in olive oil. It acts on the endocannabinoid system by modulating cannabinoid receptors CB1 and CB2, as well as other non-cannabinoid targets such as GPR55 and TRPV1, to reduce neuronal hyperexcitability. Produced under Good Manufacturing Practice (GMP) protocols, it is administered as an oral or sublingual oil and has demonstrated efficacy in clinical studies for treatment-resistant epilepsy in children and adolescents.
- Brand names
- PANAXOLCANNDOCTikvaUltra HealthSALUS
- Other names
- CBD-enriched medical cannabis oil20:1 CBD:THC medical cannabis oil
02
Targets
CNR1 (Cannabinoid receptor 1)CNR2 (Cannabinoid receptor type 2)GPR55 (G protein-coupled receptor 55)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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